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  1. Research article

    Effect of memantine on post-operative cognitive dysfunction after cardiac surgeries: a randomized clinical trial

    Post-operative cognitive dysfunction (POCD) is an important complication of cardiac surgeries. Glutamate plays a critical role in physiologic and pathologic conditions in the brain. Due to the role of glutamat...

    Saba Ghaffary, Padideh Ghaeli, Azita Hajhossein Talasaz, Abbasali Karimi, Maryam Noroozian, Abbas Salehiomran and Arash Jalali

    DARU Journal of Pharmaceutical Sciences 2017 25:24

    Published on: 21 November 2017

  2. Review article

    Linagliptin versus sitagliptin in patients with type 2 diabetes mellitus: a network meta-analysis of randomized clinical trials

    Diabetes is one of the most common chronic and costly diseases worldwide and type 2 diabetes is the most common type which accounts for about 90% of cases with diabetes. New medication-therapy regimens such as...

    Khosro Keshavarz, Farhad Lotfi, Ehsan Sanati, Mahmood Salesi, Amir Hashemi-Meshkini, Mojtaba Jafari, Mohammad M. Mojahedian, Behzad Najafi and Shekoufeh Nikfar

    DARU Journal of Pharmaceutical Sciences 2017 25:23

    Published on: 25 October 2017

  3. Research article

    Beneficial effects of Heqi san on rat model of polycystic ovary syndrome through the PI3K/AKT pathway

    Heqi San, a traditional Chinese medicine (TCM) has been reported to regulate hormone levels in patients with metabolic disease, suggesting a potential clinical application. In the current study, we aimed to el...

    Hengxia Zhao, Daocheng Zhou, Ye Chen, Deliang Liu, Shufang Chu and Shimao Zhang

    DARU Journal of Pharmaceutical Sciences 2017 25:21

    Published on: 11 October 2017

  4. Research article

    Sustained-release study on Exenatide loaded into mesoporous silica nanoparticles: in vitro characterization and in vivo evaluation

    Exenatide (EXT), the first glucagon-like peptide-1 receptor agonist, has been approved as an adjunctive therapy for patients with type 2 diabetes. Due to EXT’s short half-life, EXT must be administrated by con...

    Cuiwei Chen, Hongyue Zheng, Junjun Xu, Xiaowei Shi, Fanzhu Li and Xuanshen Wang

    DARU Journal of Pharmaceutical Sciences 2017 25:20

    Published on: 4 September 2017

  5. Research article

    Formulation of an aloe-based product according to Iranian traditional medicine and development of its analysis method

    Currently, people are more interested to traditional medicine. The traditional formulations should be converted to modern drug delivery systems to be more acceptable for the patients. In the present investigat...

    Elham Moein, Homa Hajimehdipoor, Tayebeh Toliyat, Rasool Choopani and Maryam Hamzeloo-Moghadam

    DARU Journal of Pharmaceutical Sciences 2017 25:19

    Published on: 29 August 2017

  6. Research article

    Pinus densiflora needle supercritical fluid extract suppresses the expression of pro-inflammatory mediators iNOS, IL-6 and IL-1β, and activation of inflammatory STAT1 and STAT3 signaling proteins in bacterial lipopolysaccharide-challenged murine macrophages

    Regulation of a persistently-activated inflammatory response in macrophages is an important target for treatment of various chronic diseases. Pine needle extracts are well known to have potent immunomodulatory...

    Thamizhiniyan Venkatesan, Young-Woong Choi, Jennifer Lee and Young-Kyoon Kim

    DARU Journal of Pharmaceutical Sciences 2017 25:18

    Published on: 4 August 2017

  7. Research article

    Forensic toxicology analysis of self-poisoning suicidal deaths in Tehran, Iran; trends between 2011-2015

    Suicide ranks among the top ten causes of death in all age groups all over the world. There are many methods for committing suicide including self-poisoning, firearm and hanging. The aim of the present study w...

    Roya Kordrostami, Maryam Akhgari, Maryam Ameri, Masoud Ghadipasha and Kamran Aghakhani

    DARU Journal of Pharmaceutical Sciences 2017 25:15

    Published on: 13 June 2017

  8. Review article

    Worldwide legislative challenges related to psychoactive drugs

    The discovery of a “new” psychoactive substance is a relatively exceptional event, while the regulatory response usually involved the assessment of risks to public health and inclusion of the novel substance i...

    Carolina Negrei, Bianca Galateanu, Miriana Stan, Cristian Balalau, Mircea Lucian Bogdan Dumitru, Eren Ozcagli, Concettina Fenga, Leda Kovatsi, Domniki Fragou and Aristidis Tsatsakis

    DARU Journal of Pharmaceutical Sciences 2017 25:14

    Published on: 2 June 2017

  9. Research article

    99mTc-radiolabeled GE11-modified peptide for ovarian tumor targeting

    Ovarian cancer is a serious threat for women health and the early diagnosis of this cancer might improves the survival rate of patients. The use of the targeted radiopharmaceuticals could be a non-invasive and...

    Najmeh Rahmanian, Seyed Jalal Hosseinimehr, Ali Khalaj, Zohreh Noaparast, Seyed Mohammad Abedi and Omid Sabzevari

    DARU Journal of Pharmaceutical Sciences 2017 25:13

    Published on: 2 May 2017

  10. Research article

    Adverse drug reactions and kinetics of cisplatin excretion in urine of patients undergoing cisplatin chemotherapy and radiotherapy for head and neck cancer: a prospective study

    Cisplatin is a high-potency anticancer agent; however, it causes significant adverse drug reactions (ADRs). Potential pharmacokinetic markers must be studied to predict or prevent cisplatin-induced ADRs and ac...

    Marília Berlofa Visacri, Eder de Carvalho Pincinato, Graziele Baldan Ferrari, Júlia Coelho França Quintanilha, Priscila Gava Mazzola, Carmen Silvia Passos Lima and Patricia Moriel

    DARU Journal of Pharmaceutical Sciences 2017 25:12

    Published on: 24 April 2017

  11. Research article

    Combination of sofosbuvir, pegylated-interferon and ribavirin for treatment of hepatitis C virus genotype 1 infection: a systematic review and meta-analysis

    Hepatitis C virus (HCV) infection is an important cause of chronic liver disease which has been affected 3% of world’s population. Some studies have shown that adding Sofosbuvir (SOF), an HCV polymerase inhibi...

    Fardin Dolatimehr, Hamidreza Karimi-Sari, Mohammad Saeid Rezaee-Zavareh, Seyed Moayed Alavian, Bita Behnava, Mohammad Gholami-Fesharaki and Heidar Sharafi

    DARU Journal of Pharmaceutical Sciences 2017 25:11

    Published on: 20 April 2017

  12. Review article

    A guide to acquired vitamin K coagulophathy diagnosis and treatment: the Russian perspective

    Physicians often come across with cases of vitamin K antagonists–dependent coagulopathy for reasons such as accidental use of the vitamin K antagonists (VKA), excessive administration of prescribed anticoagula...

    Valery V. Wojciechowski, Daniela Calina, Konstantinos Tsarouhas, Alexander V. Pivnik, Alexander A. Sergievich, Vladimir V. Kodintsev, Ekaterina A. Filatova, Eren Ozcagli, Anca Oana Docea, Andreea Letitia Arsene, Eliza Gofita, Christina Tsitsimpikou, Aristidis M. Tsatsakis and Kirill S. Golokhvast

    DARU Journal of Pharmaceutical Sciences 2017 25:10

    Published on: 17 April 2017

  13. Editorial

    Health risks associated with the pharmaceuticals in wastewater

    The overwhelming population growth in recent decades and water crisis along with limited and uneven geographical distribution of fresh water resources is a growing challenge for the economic and human developm...

    Nasser Nassiri Koopaei and Mohammad Abdollahi

    DARU Journal of Pharmaceutical Sciences 2017 25:9

    Published on: 12 April 2017

  14. Research article

    Improvement of memory and learning by intracerebroventricular microinjection of T3 in rat model of ischemic brain stroke mediated by upregulation of BDNF and GDNF in CA1 hippocampal region

    Ischemic stroke is a common leading cause of death and disability with lack of effective therapies. In this study, T3 was intra-ventricularly injected to evaluate gene expression and protein concentration of a...

    Tahmineh Mokhtari, Mohammad Akbari, Fatemeh Malek, Iraj Ragerdi Kashani, Tayebeh Rastegar, Farshid Noorbakhsh, Mahmoud Ghazi-Khansari, Fatemeh Attari and Gholamreza Hassanzadeh

    DARU Journal of Pharmaceutical Sciences 2017 25:4

    Published on: 15 February 2017

  15. Research article

    Simultaneous detection of bovine and porcine DNA in pharmaceutical gelatin capsules by duplex PCR assay for Halal authentication

    In the pharmaceutical industry, hard- and soft-shelled capsules are typically made from gelatin, commonly derived from bovine and porcine sources. To ensure that pharmaceutical products comply with halal regul...

    Jafar Nikzad, Soraya Shahhosseini, Maryam Tabarzad, Nastaran Nafissi-Varcheh and Maryam Torshabi

    DARU Journal of Pharmaceutical Sciences 2017 25:3

    Published on: 14 February 2017

  16. Review article

    New horizons in treatment of osteoporosis

    Prevalence of osteoporosis is increasing both in developed and developing countries. Due to rapid growth in the burden and cost of osteoporosis, worldwide, it seems reasonable to focus on the reduction of frac...

    Ozra Tabatabaei-Malazy, Pooneh Salari, Patricia Khashayar and Bagher Larijani

    DARU Journal of Pharmaceutical Sciences 2017 25:2

    Published on: 7 February 2017

  17. Research article

    Budget impact analysis of vaccination against Haemophilus influenzae type b as a part of a Pentavalent vaccine in the childhood immunization schedule of Iran

    Health decision makers need to know the impact of the development of a new intervention on the public health and health care costs so that they can plan for economic and financial objectives. The aim of this s...

    Fatemeh Teimouri, Abbas Kebriaeezadeh, Seyed Mohsen Zahraei, Mohammadmahdi Gheiratian and Shekoufeh Nikfar

    DARU Journal of Pharmaceutical Sciences 2017 25:1

    Published on: 14 January 2017

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