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  1. Research article

    Expression, purification and biological activity assessment of romiplostim biosimilar peptibody

    Romiplostim is a peptibody analogue of thrombopoietin (TPO) which regulates platelet production. This molecule consists of two main parts: Peptide sequences which like wild type TPO, mimics stimulation of TPO ...

    Shima Fayaz, Pezhman Fard-Esfahani, Majid Golkar, Mojgan Allahyari and Sedigheh Sadeghi

    DARU Journal of Pharmaceutical Sciences 2016 24:18

    Published on: 11 July 2016

  2. Research article

    Crocin suppresses multidrug resistance in MRP overexpressing ovarian cancer cell line

    Crocin, one of the main constituents of saffron extract, has numerous biological effects such as anti-cancer effects. Multidrug resistance-associated proteins 1 and 2 (MRP1 and MRP2) are important elements in ...

    Shadi Mahdizadeh, Gholamreza Karimi, Javad Behravan, Sepideh Arabzadeh, Hermann Lage and Fatemeh Kalalinia

    DARU Journal of Pharmaceutical Sciences 2016 24:17

    Published on: 24 June 2016

  3. Research article

    Effects of phloretin on oxidative and inflammatory reaction in rat model of cecal ligation and puncture induced sepsis

    Sepsis is a debilitating systemic disease and described as a severe and irregular systemic inflammatory reaction syndrome (SIRS) against infection. We employed CLP (Cecal Ligation and Puncture) model in rats t...

    Mehdi Aliomrani, Mohammad Reza Sepand, Hamid Reza Mirzaei, Ali Reza kazemi, Saeid Nekonam and Omid Sabzevari

    DARU Journal of Pharmaceutical Sciences 2016 24:15

    Published on: 6 May 2016

  4. Research article

    High azithromycin concentration in lungs by way of bovine serum albumin microspheres as targeted drug delivery: lung targeting efficiency in albino mice

    Following administration, the antibiotic travels freely through the body and also accumulates in other parts apart from the infection site. High dosage and repeated ingestion of antibiotics in the treatment of...

    Balakeshwa Ramaiah, Sree Harsha Nagaraja, Usha Ganganahalli Kapanigowda, Prakash Rao Boggarapu and Rajarajan Subramanian

    DARU Journal of Pharmaceutical Sciences 2016 24:14

    Published on: 5 May 2016

  5. Research article

    Preliminary investigation of the effects of topical mixture of Lawsonia inermis L. and Ricinus communis L. leaves extract in treatment of osteoarthritis using MIA model in rats

    Many plants have been introduced in Iranian traditional medicine for treatment of different joint problems including knee pain. Topical application of the mixture of Lawsonia inermis L. leaves (Henna) with aqueou...

    Atousa Ziaei, Shamim Sahranavard, Mohammad Javad Gharagozlou and Mehrdad Faizi

    DARU Journal of Pharmaceutical Sciences 2016 24:12

    Published on: 3 May 2016

  6. Research article

    A model for priority setting of health technology assessment: the experience of AHP-TOPSIS combination approach

    In recent times, the use of health technologies in the diagnosis and treatment of diseases experienced considerable and accelerated growth. The goal of the present study was to describe the designated pilot MC...

    Mohammadreza Mobinizadeh, Pouran Raeissi, Amir Ashkan Nasiripour, Alireza Olyaeemanesh and Seyed Jamaleddin Tabibi

    DARU Journal of Pharmaceutical Sciences 2016 24:10

    Published on: 11 April 2016

  7. Letter to the Editor

    Osmolarity: A hidden factor in Nanotoxicology 

    In the field of drug delivery, long circulating nanocarriers in the blood have many advantages such as targeted drug delivery and sustained release. Based on our current knowledge, evaluation of the effect of ...

    Saeid Moayyedi, Omid Mashinchian and Rassoul Dinarvand

    DARU Journal of Pharmaceutical Sciences 2016 24:9

    Published on: 22 March 2016

  8. Research article

    Characterization and pharmacological potential of Lactobacillus sakei 1I1 isolated from fresh water fish Zacco koreanus

    There are still a large variety of microorganisms among aquatic animals which have not been explored for their pharmacological potential. Hence, present study was aimed to isolate and characterize a potent lac...

    Vivek K. Bajpai, Jeong-Ho Han, Gyeong-Jun Nam, Rajib Majumder, Chanseo Park, Jeongheui Lim, Woon Kee Paek, Irfan A. Rather and Yong-Ha Park

    DARU Journal of Pharmaceutical Sciences 2016 24:8

    Published on: 15 March 2016

  9. Research article

    Does pharmacist-supervised intervention through pharmaceutical care program influence direct healthcare cost burden of newly diagnosed diabetics in a tertiary care teaching hospital in Nepal: a non-clinical randomised controlled trial approach

    Cost is a vital component for people with chronic diseases as treatment is expected to be long or even lifelong in some diseases. Pharmacist contributions in decreasing the healthcare cost burden of chronic pa...

    Dinesh Kumar Upadhyay, Mohamed Izham Mohamed Ibrahim, Pranaya Mishra, Vijay M. Alurkar and Mukhtar Ansari

    DARU Journal of Pharmaceutical Sciences 2016 24:6

    Published on: 29 February 2016

  10. Research article

    A novel approach for inventory problem in the pharmaceutical supply chain

    In pharmaceutical enterprises, keeping up with global market conditions is possible with properly selected supply chain management policies. Generally; demand-driven classical supply chain model is used in the...

    Gökçe Candan and Harun Reşit Yazgan

    DARU Journal of Pharmaceutical Sciences 2016 24:4

    Published on: 24 February 2016

  11. Reviewer acknowledgement

    Acknowledgement of manuscript reviewers 2015

    The editor of DARU Journal of Pharmaceutical Sciences would like to thank all our reviewers who have contributed to the journal in Volume 23 (2015).

    Mohammad Abdollahi, Mohammad Ali Faramarzi, Alireza Foroumadi, Kambiz Gilani, Hossein Khalili, Mahnaz Khanavi, Ali Akbar Moghadamnia, Morteza Mahmoudi, Shekoufeh Nikfar, Ali Nokhodchi, Roja Rahimi, Mohammad Reza Rouini and Alireza Vatanara

    DARU Journal of Pharmaceutical Sciences 2016 24:5

    Published on: 24 February 2016

  12. Review article

    Women-only drug treatment services and needs in Iran: the first review of current literature

    Iran (Persia) has a women-only drug treatment system. However, literature is not documented. The current study aimed to review the development of women-only drug treatment and harm reduction services (WODTHRS) an...

    Zahra Alam-mehrjerdi, Reza Daneshmand, Mercedeh Samiei, Roya Samadi, Mohammad Abdollahi and Kate Dolan

    DARU Journal of Pharmaceutical Sciences 2016 24:3

    Published on: 18 February 2016

    The Erratum to this article has been published in DARU Journal of Pharmaceutical Sciences 2016 24:19

  13. Research article

    Comparative Pharmacokinetics of three major bioactive components in rats after oral administration of Typhae Pollen-Trogopterus Feces drug pair before and after compatibility

    Typhae Pollen (TP) and Trogopterus Feces (TF) are well-known traditional medicine in china which widely used for thousands of years as drug pair called Shixiao San for treatment of blood stasis syndrome, speci...

    Huiting Zeng, Ping Xue, Shulan Su, Xiaochen Huang, Erxin Shang, Jianming Guo, Dawei Qian, Yuping Tang and Jin-ao Duan

    DARU Journal of Pharmaceutical Sciences 2016 24:2

    Published on: 20 January 2016

  14. Research article

    Two COX-2 inhibitors induce apoptosis in human erythroleukemia K562cells by modulating NF-κB and FHC pathways

    Leukemia is distinguished by abnormal proliferation of leukocytes. Although there has been some progress in developing novel cancer therapies, no significant improvement was observed in the overall survival ra...

    Shaghayegh Norouzi, Mahnaz Norouzi, Mohsen Amini, Amir Amanzadeh, Mohamad Nabiuni, Saeed Irian and Mona Salimi

    DARU Journal of Pharmaceutical Sciences 2016 24:1

    Published on: 7 January 2016

  15. Research Article

    Cost-effectiveness and cost-utility analysis of OTC use of simvastatin 10 mg for the primary prevention of myocardial infarction in Iranian men

    Several clinical trials and meta-analyses have shown the advantageous effects of statins in populations with different levels of cardiovascular disease (CVD) risk. Considering the increasing cardiovascular ris...

    Mohammadreza Amirsadri and Abbas Hassani

    DARU Journal of Pharmaceutical Sciences 2015 23:56

    Published on: 30 December 2015

  16. Research article

    Cardanol isolated from Thai Apis mellifera propolis induces cell cycle arrest and apoptosis of BT-474 breast cancer cells via p21 upregulation

    Cardanol was previously reported to be an antiproliferative compound purified from Thai Apis mellifera propolis. By morphology, it could induce the cell death to many cancer cell lines but not the control (non-tr...

    Sureerat Buahorm, Songchan Puthong, Tanapat Palaga, Kriengsak Lirdprapamongkol, Preecha Phuwapraisirisan, Jisnuson Svasti and Chanpen Chanchao

    DARU Journal of Pharmaceutical Sciences 2015 23:55

    Published on: 22 December 2015

  17. Research article

    Comparison of the effects of Crataegus oxyacantha extract, aerobic exercise and their combination on the serum levels of ICAM-1 and E-Selectin in patients with stable angina pectoris

    Adhesion molecules play an important role in the development and progression of coronary atherosclerosis. The aim of this study was comparing the effect of Cratagol herbal tablet, aerobic exercise and their co...

    Leila Jalaly, Gholamreza Sharifi, Mohammad Faramarzi, Alireza Nematollahi, Mahmoud Rafieian-kopaei, Masoud Amiri and Fariborz Moattar

    DARU Journal of Pharmaceutical Sciences 2015 23:54

    Published on: 19 December 2015

  18. Review article

    Blessings in disguise: a review of phytochemical composition and antimicrobial activity of plants belonging to the genus Eryngium

    Medicinal and edible plants play a crucial role in the prevention and/or mitigation of different human diseases from ancient times to today. In folk medicine, there are different plants used for infectious dis...

    Sinem Aslan Erdem, Seyed Fazel Nabavi, Ilkay Erdogan Orhan, Maria Daglia, Morteza Izadi and Seyed Mohammad Nabavi

    DARU Journal of Pharmaceutical Sciences 2015 23:53

    Published on: 14 December 2015

  19. Research article

    Preventive effects of phenylethanol glycosides from Cistanche tubulosa on bovine serum albumin-induced hepatic fibrosis in rats

    Cistanche tubulosa is a traditional Chinese herbal medicine that is widely used for regulating immunity. Phenyl ethanol glycosides (CPhGs) from this plant are the primarily efficacious...

    Shu-Ping You, Jun Zhao, Long Ma, Mukaram Tudimat, Shi-Lei Zhang and Tao Liu

    DARU Journal of Pharmaceutical Sciences 2015 23:52

    Published on: 9 December 2015

  20. Editorial

    The Persian methamphetamine use in methadone treatment in Iran: implication for prevention and treatment in an upper-middle income country

    As the most populated Persian Gulf country in West Asia, methamphetamine use in methadone maintenance treatment (MMT) is a new health concern in Iran. Methamphetamine use in MMT can originate in methadone misc...

    Zahra Alam-mehrjerdi and Mohammad Abdollahi

    DARU Journal of Pharmaceutical Sciences 2015 23:51

    Published on: 17 November 2015

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