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  1. Content type: Research article

    Leukemia is distinguished by abnormal proliferation of leukocytes. Although there has been some progress in developing novel cancer therapies, no significant improvement was observed in the overall survival ra...

    Authors: Shaghayegh Norouzi, Mahnaz Norouzi, Mohsen Amini, Amir Amanzadeh, Mohamad Nabiuni, Saeed Irian and Mona Salimi

    Citation: DARU Journal of Pharmaceutical Sciences 2016 24:1

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  2. Content type: Research Article

    Several clinical trials and meta-analyses have shown the advantageous effects of statins in populations with different levels of cardiovascular disease (CVD) risk. Considering the increasing cardiovascular ris...

    Authors: Mohammadreza Amirsadri and Abbas Hassani

    Citation: DARU Journal of Pharmaceutical Sciences 2015 23:56

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  3. Content type: Research article

    Cardanol was previously reported to be an antiproliferative compound purified from Thai Apis mellifera propolis. By morphology, it could induce the cell death to many cancer cell lines but not the control (non-tr...

    Authors: Sureerat Buahorm, Songchan Puthong, Tanapat Palaga, Kriengsak Lirdprapamongkol, Preecha Phuwapraisirisan, Jisnuson Svasti and Chanpen Chanchao

    Citation: DARU Journal of Pharmaceutical Sciences 2015 23:55

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  4. Content type: Research article

    Adhesion molecules play an important role in the development and progression of coronary atherosclerosis. The aim of this study was comparing the effect of Cratagol herbal tablet, aerobic exercise and their co...

    Authors: Leila Jalaly, Gholamreza Sharifi, Mohammad Faramarzi, Alireza Nematollahi, Mahmoud Rafieian-kopaei, Masoud Amiri and Fariborz Moattar

    Citation: DARU Journal of Pharmaceutical Sciences 2015 23:54

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  5. Content type: Review article

    Medicinal and edible plants play a crucial role in the prevention and/or mitigation of different human diseases from ancient times to today. In folk medicine, there are different plants used for infectious dis...

    Authors: Sinem Aslan Erdem, Seyed Fazel Nabavi, Ilkay Erdogan Orhan, Maria Daglia, Morteza Izadi and Seyed Mohammad Nabavi

    Citation: DARU Journal of Pharmaceutical Sciences 2015 23:53

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  6. Content type: Research article

    Cistanche tubulosa is a traditional Chinese herbal medicine that is widely used for regulating immunity. Phenyl ethanol glycosides (CPhGs) from this plant are the primarily efficacious...

    Authors: Shu-Ping You, Jun Zhao, Long Ma, Mukaram Tudimat, Shi-Lei Zhang and Tao Liu

    Citation: DARU Journal of Pharmaceutical Sciences 2015 23:52

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  7. Content type: Editorial

    As the most populated Persian Gulf country in West Asia, methamphetamine use in methadone maintenance treatment (MMT) is a new health concern in Iran. Methamphetamine use in MMT can originate in methadone misc...

    Authors: Zahra Alam-mehrjerdi and Mohammad Abdollahi

    Citation: DARU Journal of Pharmaceutical Sciences 2015 23:51

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  8. Content type: Research article

    Both omeprazole and its S enantiomer (esomeprazole) have been available and used to treat  symptoms of gastroesophageal reflux disease (GERD) and conditions associated with excessive stomach acid secretion for...

    Authors: Waheed Asghar, Elliot Pittman and Fakhreddin Jamali

    Citation: DARU Journal of Pharmaceutical Sciences 2015 23:50

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  9. Content type: Research article

    The poor ocular bioavailability of the conventional eye drops is due to lack of corneal permeability, nasolacrimal drainage and metabolic degradation. To overcome this issue, drug encapsulated in mucoadhesive ...

    Authors: Usha Ganganahalli Kapanigowda, Sree Harsha Nagaraja, Balakeshwa Ramaiah and Prakash Rao Boggarapu

    Citation: DARU Journal of Pharmaceutical Sciences 2015 23:49

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  10. Content type: Research article

    The present study was designed to investigate the efficacy of a new formulation of alone, purified cannabidiol (CBD) (>98 %), the main non-psychotropic cannabinoid of Cannabis sativa, as a topical treatment in...

    Authors: Sabrina Giacoppo, Maria Galuppo, Federica Pollastro, Gianpaolo Grassi, Placido Bramanti and Emanuela Mazzon

    Citation: DARU Journal of Pharmaceutical Sciences 2015 23:48

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  11. Content type: Review article

    Multiple organ dysfunction syndrome (MODS) and nosocomial infection following trauma-hemorrhage are among the most important causes of mortality in hemorrhagic shock patients. Dysregulation of the immune syste...

    Authors: Javad Motaharinia, Farhad Etezadi, Azadeh Moghaddas and Mojtaba Mojtahedzadeh

    Citation: DARU Journal of Pharmaceutical Sciences 2015 23:47

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  12. Content type: Research article

    Repaglinide is an efficient anti-diabetic drug which is prescribed widely as multi-dosage oral daily regimens. Due to the low compliance inherent to each multi-dosage regimen, development of prolonged-release ...

    Authors: Hossein Ali Ebrahimi, Yousef Javadzadeh, Mehrdad Hamidi and Mohammad Barzegar Jalali

    Citation: DARU Journal of Pharmaceutical Sciences 2015 23:46

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  13. Content type: Review article

    Diabetes mellitus is a leading cause of morbidity and mortality worldwide. Studies have shown that Zinc has numerous beneficial effects in both type-1 and type-2 diabetes. We aim to evaluate the literature on ...

    Authors: Priyanga Ranasinghe, Shehani Pigera, Priyadarshani Galappatthy, Prasad Katulanda and Godwin R. Constantine

    Citation: DARU Journal of Pharmaceutical Sciences 2015 23:44

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  14. Content type: Research Article

    Superparamagnetic iron oxide nanoparticles (SPIONs) are the most commonly used negative MRI contrast agent which affect the transverse (T2) relaxation time. The aim of the present study was to investigate the imp...

    Authors: Maryam Khalkhali, Kobra Rostamizadeh, Somayeh Sadighian, Farhad Khoeini, Mehran Naghibi and Mehrdad Hamidi

    Citation: DARU Journal of Pharmaceutical Sciences 2015 23:45

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  15. Content type: Research article

    Diabetes mellitus is characterized jointly by hyperglycemia and hyperinsulinemia that make insulin more prone to be glycated and evolve insulin advanced glycation end products (Insulin- AGE). Here, we report t...

    Authors: Manijheh Sabokdast, Mehran Habibi-Rezaei, Ali Akbar Moosavi-Movahedi, Maryam Ferdousi, Effat Azimzadeh-Irani and Najmeh Poursasan

    Citation: DARU Journal of Pharmaceutical Sciences 2015 23:42

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  16. Content type: Research

    The present work objective was to prepare and to observe the effect of ethylene glycol dimethacrylate on swelling and on drug release behavior of pH-sensitive acrylic acid–polyvinyl alcohol hydrogel.

    Authors: Muhammad Faheem Akhtar, Nazar Muhammad Ranjha and Muhammad Hanif

    Citation: DARU Journal of Pharmaceutical Sciences 2015 23:41

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  17. Content type: Research

    Human epidermal growth-factor receptor (HER)-2 is overexpressed in 25 % of breast-cancers and is associated with an aggressive form of the disease with significantly shortened disease free and overall survival...

    Authors: Alessio Di Luca, Michael Henry, Paula Meleady and Robert O’Connor

    Citation: DARU Journal of Pharmaceutical Sciences 2015 23:40

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  18. Content type: Research

    Thallium (Tl) is a toxic heavy metal that exists in nature. Tl poisoning (thallotoxicosis) may occur in opioid addicts. This study was designed to evaluate the frequency and level of urinary Tl in opioid abuse...

    Authors: Amir Ghaderi, Naser Vahdati-Mashhadian, Zohreh Oghabian, Valiallah Moradi, Reza Afshari and Omid Mehrpour

    Citation: DARU Journal of Pharmaceutical Sciences 2015 23:39

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  19. Content type: Research

    NF-E2-related factor2 (Nrf2)-antioxidant response element (ARE) signaling pathway is the major defensive mechanism against oxidative stress and is up regulated by specific antioxidants and oxidants to comprise...

    Authors: Paria Motahari, Majid Sadeghizadeh, Mehrdad Behmanesh, Shaghayegh Sabri and Fatemeh Zolghadr

    Citation: DARU Journal of Pharmaceutical Sciences 2015 23:38

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  20. Content type: Research

    Dehydroandrographolide (DA) is one of major active components in the well-known oriental herbal medicine Andrographis paniculata (Burm.f) Nees which belongs to the Acanthaceae family. DA is used for the treatment...

    Authors: Wen-Bi Xiong, Zhen-Jun Shao, Yao Xiong, Jian Chen, Yun Sun, Ling Zhu and Li-Ming Zhou

    Citation: DARU Journal of Pharmaceutical Sciences 2015 23:37

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  21. Content type: Research article

    Recent studies have been explained the role of lipoxygenases (LOX) in the origin of cancer. Among the lipoxygenases, the 5-LOX, 12-LOX and 15-LOX are more important in the cause of neoplastic disorders. In the...

    Authors: Alireza Aliabadi, Ahmad Mohammadi-Farani, Zeinab Hosseinzadeh, Hamid Nadri, Alireza Moradi and Farahnaz Ahmadi

    Citation: DARU Journal of Pharmaceutical Sciences 2015 23:36

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  22. Content type: Research

    Cordyceps militaris has been used as a traditional medicine in Asian countries for a long time. Different types of Cordyceps extract were reported to have various pharmacological activ...

    Authors: Hwan Hee Lee, Seulki Lee, Kanghyo Lee, Yu Su Shin, Hyojeung Kang and Hyosun Cho

    Citation: DARU Journal of Pharmaceutical Sciences 2015 23:35

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  23. Content type: Research

    Klebsiella pneumoniae is one of the most important opportunistic pathogens causing serious complications in patients in hospitals and community. The clinical significance of K. pneumoniae is ma...

    Authors: Leila Vali, Ali A. Dashti, Mehrez M. Jadaon and Sherief El-Shazly

    Citation: DARU Journal of Pharmaceutical Sciences 2015 23:34

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  24. Content type: Research

    The beneficial effects of curcumin which includes its antioxidant, anti-inflammatory and cancer chemo-preventive properties have been identified. Little information is available regarding the optimal dose and ...

    Authors: Fatemeh Attari, Maryam Zahmatkesh, Hadi Aligholi, Shahram Ejtemaei Mehr, Mohammad Sharifzadeh, Ali Gorji, Tahmineh Mokhtari, Mojtaba Khaksarian and Gholamreza Hassanzadeh

    Citation: DARU Journal of Pharmaceutical Sciences 2015 23:33

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  25. Content type: Research article

    Previous studies suggest that chemical constituents present in Pinus eldarica Medw (P. eldarica) nut possess antioxidant properties that may positively influence lipid profile.

    Authors: Hasan Fallah Huseini, Maryam Sotoudeh Anvari, Yaser Tajallizadeh khoob, Shahram Rabbani, Farshad Sharifi, Seyed Masoud Arzaghi and Hossein Fakhrzadeh

    Citation: DARU Journal of Pharmaceutical Sciences 2015 23:32

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  26. Content type: Research article

    Carvedilol belongs to a group of medicines termed non-selective beta-adrenergic blocking agents. In the presented approach, a practical and environmentally friendly microextraction method based on the applicat...

    Authors: Mohsen Zeeb and Behrooz Mirza

    Citation: DARU Journal of Pharmaceutical Sciences 2015 23:30

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  27. Content type: Research article

    MMP-2 enzyme is a kind of matrix metalloproteinases that digests the denatured collagens and gelatins. It is highly involved in the process of tumor invasion and has been considered as a promising target for c...

    Authors: Maryam Abbasi, Fatemeh Ramezani, Maryam Elyasi, Hojjat Sadeghi-Aliabadi and Massoud Amanlou

    Citation: DARU Journal of Pharmaceutical Sciences 2015 23:29

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  28. Content type: Research article

    Nanoparticles (NPs) play an important role in anticancer delivery systems. Surface modified NPs with hydrophilic polymers such as human serum albumin (HSA) have long half-life in the blood circulation system.

    Authors: Mehdi Esfandyari-Manesh, Seyed Hossein Mostafavi, Reza Faridi Majidi, Mona Noori Koopaei, Nazanin Shabani Ravari, Mohsen Amini, Behrad Darvishi, Seyed Nasser Ostad, Fatemeh Atyabi and Rassoul Dinarvand

    Citation: DARU Journal of Pharmaceutical Sciences 2015 23:28

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  29. Content type: Research article

    Dried fruits of Berberis crataegina (Berberidaceae) have been frequently consumed as food garniture in Turkish cuisine, while its fruit paste has been used to increase stamina and in particular to prevent from ca...

    Authors: Mohammad Charehsaz, Hande Sipahi, Engin Celep, Aylin Üstündağ, Özge Cemiloğlu Ülker, Yalçın Duydu, Ahmet Aydın and Erdem Yesilada

    Citation: DARU Journal of Pharmaceutical Sciences 2015 23:24

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  30. Content type: Case report

    Nabiximols (Sativex) is an oromucosal spray, containing delta-9 tetrahydrocannabinol (THC) and cannabidiol (CBD), used as treatment for unresponsive spasticity in multiple sclerosis (MS) patients. Sativex is t...

    Authors: Margherita Russo, Carmela Rifici, Edoardo Sessa, Giangaetano D’Aleo, Placido Bramanti and Rocco Salvatore Calabrò

    Citation: DARU Journal of Pharmaceutical Sciences 2015 23:25

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  31. Content type: Research article

    Bacopa monnieri Linn. (Plantaginaceae), a well-known medicinal plant, is widely used in traditional medicine system. It has long been used in gastrointestinal discomfort, skin diseases, epileps...

    Authors: Talha Bin Emran, Md Atiar Rahman, Mir Muhammad Nasir Uddin, Raju Dash, Md Firoz Hossen, Mohammad Mohiuddin and Md Rashadul Alam

    Citation: DARU Journal of Pharmaceutical Sciences 2015 23:26

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  32. Content type: Research article

    Management of difficult to wean patients is a dilemma for health care system. Recently published studies demonstrated efficacy of donepezil to counteract respiratory depression in sleep apnea. However, to the ...

    Authors: Saeed Abbasi, Shadi Farsaei, Kamran Fazel, Samad EJ Golzari and Ata Mahmoodpoor

    Citation: DARU Journal of Pharmaceutical Sciences 2015 23:23

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  33. Content type: Short communication

    Tramalol overdose is disproportionately more common in Iran. In recent years, Tramadol overdose has become one of the most common causes of poisoning admissions to emergency departments in this country. To the...

    Authors: Hamid Khosrojerdi, Ghazal Alipour Talesh, Gholam Hassan Danaei, Sara Shokooh Saremi, Afrouz Adab and Reza Afshari

    Citation: DARU Journal of Pharmaceutical Sciences 2015 23:22

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  34. Content type: Research article

    Because of expanding presence of nanomaterials, there has been an increase in the exposure of humans to nanoparticles that is why nanotoxicology studies are important. A number of studies on the effects of nan...

    Authors: Somayeh Rajabi, Ali Ramazani, Mehrdad Hamidi and Tahereh Naji

    Citation: DARU Journal of Pharmaceutical Sciences 2015 23:20

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  35. Content type: Research article

    Asthma is an inflammatory condition characterized by airway hyperresponsiveness and chronic inflammation. The resolution of inflammation is an essential process to treat this condition. In this study we invest...

    Authors: Tatiane Teixeira Oliveira, Keina Maciele Campos, Ana Tereza Cerqueira-Lima, Tamires Cana Brasil Carneiro, Eudes da Silva Velozo, Ingrid Christie Alexandrino Ribeiro Melo, Eugênia Abrantes Figueiredo, Eduardo de Jesus Oliveira, Darizy Flávia Silva Amorim de Vasconcelos, Lain Carlos Pontes-de-Carvalho, Neuza Maria Alcântara-Neves and Camila Alexandrina Figueiredo

    Citation: DARU Journal of Pharmaceutical Sciences 2015 23:18

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  36. Content type: Research article

    Clinical use of selective PDE3 inhibitors as cardiotonic agents is limited because of their chronotropic and lipolytic side effects. In our previous work, we synthesized a new PDE3 inhibitor named MC2 (6-[4-(4...

    Authors: Bagher Alinejad, Reza Shafiee-Nick, Hamid Sadeghian and Ahmad Ghorbani

    Citation: DARU Journal of Pharmaceutical Sciences 2015 23:19

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  37. Content type: Research article

    Cytotoxic effects of some of the members of papaveraceae family have been reported in Iranian folk medicine. Recent reports has indicated that alkaloids fraction of opium may be responsible for its cytotoxic e...

    Authors: Monireh Afzali, Padideh Ghaeli, Mahnaz Khanavi, Maliheh Parsa, Hamed Montazeri, Mohammad Hossein Ghahremani and Seyed Nasser Ostad

    Citation: DARU Journal of Pharmaceutical Sciences 2015 23:16

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  38. Content type: Reviewer acknowledgement

    The editors of DARU Journal of Pharmaceutical Sciences would like to thank all our reviewers who have contributed to the journal in Volume 22 (2014).

    Authors: Mohammad Abdollahi, Mohammad Ali Faramarzi, Alireza Foroumadi, Kambiz Gilani, Hossein Khalili, Mahnaz Khanavi, Ali Akbar Moghadamnia, Shekoufeh Nikfar, Ali Nokhodchi, Roja Rahimi, Mohammad Reza Rouini and Alireza Vatanara

    Citation: DARU Journal of Pharmaceutical Sciences 2015 23:11

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  39. Content type: Research article

    Studies have shown that pharmaceutical care can result in favorable clinical outcomes in human immunodeficiency virus (HIV)-infected patients, however, few studies have assessed the economic impact. The object...

    Authors: Renata Cavalcanti Carnevale, Caroline de Godoi Rezende Costa Molino, Marília Berlofa Visacri, Priscila Gava Mazzola and Patricia Moriel

    Citation: DARU Journal of Pharmaceutical Sciences 2015 23:13

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  40. Content type: Research article

    The service weight is among several issues and challenges in the implementation of case-mix in developing countries, including Malaysia. The aim of this study is to develop the Malaysian Diagnosis Related Grou...

    Authors: Saad Ahmed Ali Jadoo, Syed Mohamed Aljunid, Amrizal Muhammad Nur, Zafar Ahmed and Dexter Van Dort

    Citation: DARU Journal of Pharmaceutical Sciences 2015 23:14

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  41. Content type: Research article

    Cynodon dactylon, a valuable medicinal plant, is widely used in Iranian folk medicine for the treatment of various cardiovascular diseases such as heart failure and atherosclerosis. Moreover, i...

    Authors: Hamid Soraya, Milad Moloudizargari, Shahin Aghajanshakeri, Soheil Javaherypour, Aram Mokarizadeh, Sanaz Hamedeyazdan, Hadi Esmaeli Gouvarchin Ghaleh, Peyman Mikaili and Alireza Garjani

    Citation: DARU Journal of Pharmaceutical Sciences 2015 23:10

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  42. Content type: Research article

    Gold nanoparticles now command a great deal of attention for medical applications. Despite the importance of nano-bio interfaces, interaction between peptides and proteins with gold surfaces is not still fully...

    Authors: Fatemeh Ramezani, Mostafa Habibi, Hashem Rafii-Tabar and Massoud Amanlou

    Citation: DARU Journal of Pharmaceutical Sciences 2015 23:9

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