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  1. Content type: Research article

    Treatment of the ischemic stroke has remained a major healthcare challenge. The phenolic compound, sesamol, has shown promising antioxidant and neuroprotective effects, however, fast clearance may negatively a...

    Authors: Parichehr Hassanzadeh, Fatemeh Atyabi, Rassoul Dinarvand, Ahmad-Reza Dehpour, Morteza Azhdarzadeh and Meshkat Dinarvand

    Citation: DARU Journal of Pharmaceutical Sciences 2017 25:25

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  2. Content type: Research article

    Post-operative cognitive dysfunction (POCD) is an important complication of cardiac surgeries. Glutamate plays a critical role in physiologic and pathologic conditions in the brain. Due to the role of glutamat...

    Authors: Saba Ghaffary, Padideh Ghaeli, Azita Hajhossein Talasaz, Abbasali Karimi, Maryam Noroozian, Abbas Salehiomran and Arash Jalali

    Citation: DARU Journal of Pharmaceutical Sciences 2017 25:24

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  3. Content type: Review article

    Diabetes is one of the most common chronic and costly diseases worldwide and type 2 diabetes is the most common type which accounts for about 90% of cases with diabetes. New medication-therapy regimens such as...

    Authors: Khosro Keshavarz, Farhad Lotfi, Ehsan Sanati, Mahmood Salesi, Amir Hashemi-Meshkini, Mojtaba Jafari, Mohammad M. Mojahedian, Behzad Najafi and Shekoufeh Nikfar

    Citation: DARU Journal of Pharmaceutical Sciences 2017 25:23

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  4. Content type: Research article

    The purpose of the present study is to optimize a spray-dried formulation as a model antibody regarding stability and aerodynamic property for further aerosol therapy of this group of macromolecules.

    Authors: Homa Faghihi, Abdolhosein Rouholamini Najafabadi and Alireza Vatanara

    Citation: DARU Journal of Pharmaceutical Sciences 2017 25:22

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  5. Content type: Research article

    Heqi San, a traditional Chinese medicine (TCM) has been reported to regulate hormone levels in patients with metabolic disease, suggesting a potential clinical application. In the current study, we aimed to el...

    Authors: Hengxia Zhao, Daocheng Zhou, Ye Chen, Deliang Liu, Shufang Chu and Shimao Zhang

    Citation: DARU Journal of Pharmaceutical Sciences 2017 25:21

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  6. Content type: Research article

    Exenatide (EXT), the first glucagon-like peptide-1 receptor agonist, has been approved as an adjunctive therapy for patients with type 2 diabetes. Due to EXT’s short half-life, EXT must be administrated by con...

    Authors: Cuiwei Chen, Hongyue Zheng, Junjun Xu, Xiaowei Shi, Fanzhu Li and Xuanshen Wang

    Citation: DARU Journal of Pharmaceutical Sciences 2017 25:20

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  7. Content type: Research article

    Currently, people are more interested to traditional medicine. The traditional formulations should be converted to modern drug delivery systems to be more acceptable for the patients. In the present investigat...

    Authors: Elham Moein, Homa Hajimehdipoor, Tayebeh Toliyat, Rasool Choopani and Maryam Hamzeloo-Moghadam

    Citation: DARU Journal of Pharmaceutical Sciences 2017 25:19

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  8. Content type: Research article

    Regulation of a persistently-activated inflammatory response in macrophages is an important target for treatment of various chronic diseases. Pine needle extracts are well known to have potent immunomodulatory...

    Authors: Thamizhiniyan Venkatesan, Young-Woong Choi, Jennifer Lee and Young-Kyoon Kim

    Citation: DARU Journal of Pharmaceutical Sciences 2017 25:18

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  9. Content type: Research article

    Heat shock protein90 (Hsp90) are overexpressed in tumor cells, so the inhibition of the Hsp90 ATPase activity would be a significantly effective strategy in cancer therapy.

    Authors: Maryam Abbasi, Hojjat Sadeghi-Aliabadi and Massoud Amanlou

    Citation: DARU Journal of Pharmaceutical Sciences 2017 25:17

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  10. Content type: Short Communication

    Nowadays MDMA (3,4-methylendioxymethamphetamine), known as ecstasy, is widely abused among the youth because of euphoria induction in acute exposure. However, abusers are predisposed to depression in chronic c...

    Authors: Sanaz Jamshidfar, Yalda H. Ardakani, Hoda Lavasani and Mohammadreza Rouini

    Citation: DARU Journal of Pharmaceutical Sciences 2017 25:16

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  11. Content type: Research article

    Suicide ranks among the top ten causes of death in all age groups all over the world. There are many methods for committing suicide including self-poisoning, firearm and hanging. The aim of the present study w...

    Authors: Roya Kordrostami, Maryam Akhgari, Maryam Ameri, Masoud Ghadipasha and Kamran Aghakhani

    Citation: DARU Journal of Pharmaceutical Sciences 2017 25:15

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  12. Content type: Review article

    The discovery of a “new” psychoactive substance is a relatively exceptional event, while the regulatory response usually involved the assessment of risks to public health and inclusion of the novel substance i...

    Authors: Carolina Negrei, Bianca Galateanu, Miriana Stan, Cristian Balalau, Mircea Lucian Bogdan Dumitru, Eren Ozcagli, Concettina Fenga, Leda Kovatsi, Domniki Fragou and Aristidis Tsatsakis

    Citation: DARU Journal of Pharmaceutical Sciences 2017 25:14

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  13. Content type: Research article

    Ovarian cancer is a serious threat for women health and the early diagnosis of this cancer might improves the survival rate of patients. The use of the targeted radiopharmaceuticals could be a non-invasive and...

    Authors: Najmeh Rahmanian, Seyed Jalal Hosseinimehr, Ali Khalaj, Zohreh Noaparast, Seyed Mohammad Abedi and Omid Sabzevari

    Citation: DARU Journal of Pharmaceutical Sciences 2017 25:13

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  14. Content type: Research article

    Cisplatin is a high-potency anticancer agent; however, it causes significant adverse drug reactions (ADRs). Potential pharmacokinetic markers must be studied to predict or prevent cisplatin-induced ADRs and ac...

    Authors: Marília Berlofa Visacri, Eder de Carvalho Pincinato, Graziele Baldan Ferrari, Júlia Coelho França Quintanilha, Priscila Gava Mazzola, Carmen Silvia Passos Lima and Patricia Moriel

    Citation: DARU Journal of Pharmaceutical Sciences 2017 25:12

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  15. Content type: Research article

    Hepatitis C virus (HCV) infection is an important cause of chronic liver disease which has been affected 3% of world’s population. Some studies have shown that adding Sofosbuvir (SOF), an HCV polymerase inhibi...

    Authors: Fardin Dolatimehr, Hamidreza Karimi-Sari, Mohammad Saeid Rezaee-Zavareh, Seyed Moayed Alavian, Bita Behnava, Mohammad Gholami-Fesharaki and Heidar Sharafi

    Citation: DARU Journal of Pharmaceutical Sciences 2017 25:11

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  16. Content type: Review article

    Physicians often come across with cases of vitamin K antagonists–dependent coagulopathy for reasons such as accidental use of the vitamin K antagonists (VKA), excessive administration of prescribed anticoagula...

    Authors: Valery V. Wojciechowski, Daniela Calina, Konstantinos Tsarouhas, Alexander V. Pivnik, Alexander A. Sergievich, Vladimir V. Kodintsev, Ekaterina A. Filatova, Eren Ozcagli, Anca Oana Docea, Andreea Letitia Arsene, Eliza Gofita, Christina Tsitsimpikou, Aristidis M. Tsatsakis and Kirill S. Golokhvast

    Citation: DARU Journal of Pharmaceutical Sciences 2017 25:10

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  17. Content type: Editorial

    The overwhelming population growth in recent decades and water crisis along with limited and uneven geographical distribution of fresh water resources is a growing challenge for the economic and human developm...

    Authors: Nasser Nassiri Koopaei and Mohammad Abdollahi

    Citation: DARU Journal of Pharmaceutical Sciences 2017 25:9

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  18. Content type: Research article

    Tributyltin (IV) compounds are promising candidates for drug development. In the current study, we evaluated in-vitro and in-silico profile of carboxylate derivatives of tributyltin (IV) complexes.

    Authors: Durdana Waseem, Arshad Farooq Butt, Ihsan-ul Haq, Moazzam Hussain Bhatti and Gul Majid Khan

    Citation: DARU Journal of Pharmaceutical Sciences 2017 25:8

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  19. Content type: Letter to the Editor

    Pharmacogenomics and pharmacoproteomics are new sciences that their goal is achieving therapeutics with maximum results and minimal side effects for each individual due to the pattern of his genome and proteome.

    Authors: Reihaneh Moeini, Zahra Memariani, Parvin Pasalar and Narjes Gorji

    Citation: DARU Journal of Pharmaceutical Sciences 2017 25:7

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  20. Content type: Research article

    Mucoadhesion is an important property that helps oral drug delivery system to remain attached with buccal mucosa and hence to improve the delivery of the drug. The current study was designed to achieve the thi...

    Authors: Muhammad Hanif and Muhammad Zaman

    Citation: DARU Journal of Pharmaceutical Sciences 2017 25:6

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  21. Content type: Research article

    Methamphetamine abuse is a worldwide health concern. Methamphetamine causes health hazards in many vital organs. It can cause damage to cardiac tissue via catecholamines release. Methamphetamine related deaths...

    Authors: Maryam Akhgari, Homeira Mobaraki and Afshar Etemadi-Aleagha

    Citation: DARU Journal of Pharmaceutical Sciences 2017 25:5

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  22. Content type: Research article

    Ischemic stroke is a common leading cause of death and disability with lack of effective therapies. In this study, T3 was intra-ventricularly injected to evaluate gene expression and protein concentration of a...

    Authors: Tahmineh Mokhtari, Mohammad Akbari, Fatemeh Malek, Iraj Ragerdi Kashani, Tayebeh Rastegar, Farshid Noorbakhsh, Mahmoud Ghazi-Khansari, Fatemeh Attari and Gholamreza Hassanzadeh

    Citation: DARU Journal of Pharmaceutical Sciences 2017 25:4

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  23. Content type: Research article

    In the pharmaceutical industry, hard- and soft-shelled capsules are typically made from gelatin, commonly derived from bovine and porcine sources. To ensure that pharmaceutical products comply with halal regul...

    Authors: Jafar Nikzad, Soraya Shahhosseini, Maryam Tabarzad, Nastaran Nafissi-Varcheh and Maryam Torshabi

    Citation: DARU Journal of Pharmaceutical Sciences 2017 25:3

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  24. Content type: Review article

    Prevalence of osteoporosis is increasing both in developed and developing countries. Due to rapid growth in the burden and cost of osteoporosis, worldwide, it seems reasonable to focus on the reduction of frac...

    Authors: Ozra Tabatabaei-Malazy, Pooneh Salari, Patricia Khashayar and Bagher Larijani

    Citation: DARU Journal of Pharmaceutical Sciences 2017 25:2

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  25. Content type: Research article

    Health decision makers need to know the impact of the development of a new intervention on the public health and health care costs so that they can plan for economic and financial objectives. The aim of this s...

    Authors: Fatemeh Teimouri, Abbas Kebriaeezadeh, Seyed Mohsen Zahraei, Mohammadmahdi Gheiratian and Shekoufeh Nikfar

    Citation: DARU Journal of Pharmaceutical Sciences 2017 25:1

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  26. Content type: Research article

    Evaluations of silver in both nanoparticle (Ag-NPs) and ionic forms indicate some adverse effects on living organisms, but little is known about their potential for developmental toxicity. In this study, devel...

    Authors: Mohammad Charehsaz, Karin Sørig Hougaard, Hande Sipahi, Asiye Işın Doğan Ekici, Çiğdem Kaspar, Mustafa Culha, Ülkü Ündeğer Bucurgat and Ahmet Aydin

    Citation: DARU Journal of Pharmaceutical Sciences 2016 24:24

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  27. Content type: Editorial

    Pharmaceutical nanotechnology has generated breakthrough developments in improving health care and human life from its emergence. The biomaterials employed mainly aim at improving drug delivery systems, imagin...

    Authors: Nasser Nassiri Koopaei and Mohammad Abdollahi

    Citation: DARU Journal of Pharmaceutical Sciences 2016 24:23

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    The Erratum to this article has been published in DARU Journal of Pharmaceutical Sciences 2016 24:25

  28. Content type: Research article

    Recently flavonoids have attracted the attention of researchers in the fight against cancer. Calycopterin and xanthomicrol, are two polymethoxylated flavonoids found in the aerial parts of Dracocephalum kotschyi ...

    Authors: Seyedeh-Somayeh Zamani, Mohsen Hossieni, Mahmoud Etebari, Pirooz Salehian and Soltan Ahmad Ebrahimi

    Citation: DARU Journal of Pharmaceutical Sciences 2016 24:22

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  29. Content type: Research article

    Hyaluronic acid (HA) has been used for target-specific drug delivery because of strong affinity to CD44, a marker in which overexpressed in cancer cells and cancer stem cells. Conjugation of HA to the cytotoxi...

    Authors: Nazanin Shabani Ravari, Navid Goodarzi, Farhad Alvandifar, Mohsen Amini, Effat Souri, Mohammad Reza Khoshayand, Zahra Hadavand Mirzaie, Fatemeh Atyabi and Rassoul Dinarvand

    Citation: DARU Journal of Pharmaceutical Sciences 2016 24:21

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  30. Content type: Letter to the Editor

    We investigated the occurrence of bleeding complications in patients who underwent skin tumor surgery and compared it between Aspirin users and a placebo control group. In this double blind randomized controll...

    Authors: Arman Engheta, Shahryar Hadadi Abianeh, Ali Atri and Mehdi Sanatkarfar

    Citation: DARU Journal of Pharmaceutical Sciences 2016 24:20

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  31. Content type: Research article

    Romiplostim is a peptibody analogue of thrombopoietin (TPO) which regulates platelet production. This molecule consists of two main parts: Peptide sequences which like wild type TPO, mimics stimulation of TPO ...

    Authors: Shima Fayaz, Pezhman Fard-Esfahani, Majid Golkar, Mojgan Allahyari and Sedigheh Sadeghi

    Citation: DARU Journal of Pharmaceutical Sciences 2016 24:18

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  32. Content type: Research article

    Crocin, one of the main constituents of saffron extract, has numerous biological effects such as anti-cancer effects. Multidrug resistance-associated proteins 1 and 2 (MRP1 and MRP2) are important elements in ...

    Authors: Shadi Mahdizadeh, Gholamreza Karimi, Javad Behravan, Sepideh Arabzadeh, Hermann Lage and Fatemeh Kalalinia

    Citation: DARU Journal of Pharmaceutical Sciences 2016 24:17

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  33. Content type: Short communication

    Serum cystatin C (Cys C) has a number of advantages over serum creatinine in the evaluation of kidney function. Apart from Cys C level itself, several formulas have also been introduced in different clinical s...

    Authors: Iman Karimzadeh and Hossein Khalili

    Citation: DARU Journal of Pharmaceutical Sciences 2016 24:16

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  34. Content type: Research article

    Sepsis is a debilitating systemic disease and described as a severe and irregular systemic inflammatory reaction syndrome (SIRS) against infection. We employed CLP (Cecal Ligation and Puncture) model in rats t...

    Authors: Mehdi Aliomrani, Mohammad Reza Sepand, Hamid Reza Mirzaei, Ali Reza kazemi, Saeid Nekonam and Omid Sabzevari

    Citation: DARU Journal of Pharmaceutical Sciences 2016 24:15

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  35. Content type: Research article

    Following administration, the antibiotic travels freely through the body and also accumulates in other parts apart from the infection site. High dosage and repeated ingestion of antibiotics in the treatment of...

    Authors: Balakeshwa Ramaiah, Sree Harsha Nagaraja, Usha Ganganahalli Kapanigowda, Prakash Rao Boggarapu and Rajarajan Subramanian

    Citation: DARU Journal of Pharmaceutical Sciences 2016 24:14

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  36. Content type: Short communication

    The right to health as a basic human right- and access to medicine as a part of it- have been a matter of attention for several decades. Also the responsibilities of different parties- particularly pharmaceuti...

    Authors: Saeed Ahmadiani and Shekoufeh Nikfar

    Citation: DARU Journal of Pharmaceutical Sciences 2016 24:13

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  37. Content type: Research article

    Many plants have been introduced in Iranian traditional medicine for treatment of different joint problems including knee pain. Topical application of the mixture of Lawsonia inermis L. leaves (Henna) with aqueou...

    Authors: Atousa Ziaei, Shamim Sahranavard, Mohammad Javad Gharagozlou and Mehrdad Faizi

    Citation: DARU Journal of Pharmaceutical Sciences 2016 24:12

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  38. Content type: Research article

    In recent times, the use of health technologies in the diagnosis and treatment of diseases experienced considerable and accelerated growth. The goal of the present study was to describe the designated pilot MC...

    Authors: Mohammadreza Mobinizadeh, Pouran Raeissi, Amir Ashkan Nasiripour, Alireza Olyaeemanesh and Seyed Jamaleddin Tabibi

    Citation: DARU Journal of Pharmaceutical Sciences 2016 24:10

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  39. Content type: Letter to the Editor

    In the field of drug delivery, long circulating nanocarriers in the blood have many advantages such as targeted drug delivery and sustained release. Based on our current knowledge, evaluation of the effect of ...

    Authors: Saeid Moayyedi, Omid Mashinchian and Rassoul Dinarvand

    Citation: DARU Journal of Pharmaceutical Sciences 2016 24:9

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  40. Content type: Research article

    There are still a large variety of microorganisms among aquatic animals which have not been explored for their pharmacological potential. Hence, present study was aimed to isolate and characterize a potent lac...

    Authors: Vivek K. Bajpai, Jeong-Ho Han, Gyeong-Jun Nam, Rajib Majumder, Chanseo Park, Jeongheui Lim, Woon Kee Paek, Irfan A. Rather and Yong-Ha Park

    Citation: DARU Journal of Pharmaceutical Sciences 2016 24:8

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  41. Content type: Research article

    Cost is a vital component for people with chronic diseases as treatment is expected to be long or even lifelong in some diseases. Pharmacist contributions in decreasing the healthcare cost burden of chronic pa...

    Authors: Dinesh Kumar Upadhyay, Mohamed Izham Mohamed Ibrahim, Pranaya Mishra, Vijay M. Alurkar and Mukhtar Ansari

    Citation: DARU Journal of Pharmaceutical Sciences 2016 24:6

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  42. Content type: Reviewer acknowledgement

    The editor of DARU Journal of Pharmaceutical Sciences would like to thank all our reviewers who have contributed to the journal in Volume 23 (2015).

    Authors: Mohammad Abdollahi, Mohammad Ali Faramarzi, Alireza Foroumadi, Kambiz Gilani, Hossein Khalili, Mahnaz Khanavi, Ali Akbar Moghadamnia, Morteza Mahmoudi, Shekoufeh Nikfar, Ali Nokhodchi, Roja Rahimi, Mohammad Reza Rouini and Alireza Vatanara

    Citation: DARU Journal of Pharmaceutical Sciences 2016 24:5

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  43. Content type: Review article

    Iran (Persia) has a women-only drug treatment system. However, literature is not documented. The current study aimed to review the development of women-only drug treatment and harm reduction services (WODTHRS) an...

    Authors: Zahra Alam-mehrjerdi, Reza Daneshmand, Mercedeh Samiei, Roya Samadi, Mohammad Abdollahi and Kate Dolan

    Citation: DARU Journal of Pharmaceutical Sciences 2016 24:3

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    The Erratum to this article has been published in DARU Journal of Pharmaceutical Sciences 2016 24:19

  44. Content type: Research article

    Typhae Pollen (TP) and Trogopterus Feces (TF) are well-known traditional medicine in china which widely used for thousands of years as drug pair called Shixiao San for treatment of blood stasis syndrome, speci...

    Authors: Huiting Zeng, Ping Xue, Shulan Su, Xiaochen Huang, Erxin Shang, Jianming Guo, Dawei Qian, Yuping Tang and Jin-ao Duan

    Citation: DARU Journal of Pharmaceutical Sciences 2016 24:2

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  45. Content type: Research article

    Leukemia is distinguished by abnormal proliferation of leukocytes. Although there has been some progress in developing novel cancer therapies, no significant improvement was observed in the overall survival ra...

    Authors: Shaghayegh Norouzi, Mahnaz Norouzi, Mohsen Amini, Amir Amanzadeh, Mohamad Nabiuni, Saeed Irian and Mona Salimi

    Citation: DARU Journal of Pharmaceutical Sciences 2016 24:1

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