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  1. Research article

    Does pharmacist-supervised intervention through pharmaceutical care program influence direct healthcare cost burden of newly diagnosed diabetics in a tertiary care teaching hospital in Nepal: a non-clinical randomised controlled trial approach

    Cost is a vital component for people with chronic diseases as treatment is expected to be long or even lifelong in some diseases. Pharmacist contributions in decreasing the healthcare cost burden of chronic pa...

    Dinesh Kumar Upadhyay, Mohamed Izham Mohamed Ibrahim, Pranaya Mishra, Vijay M. Alurkar and Mukhtar Ansari

    DARU Journal of Pharmaceutical Sciences 2016 24:6

    Published on: 29 February 2016

  2. Reviewer acknowledgement

    Acknowledgement of manuscript reviewers 2015

    The editor of DARU Journal of Pharmaceutical Sciences would like to thank all our reviewers who have contributed to the journal in Volume 23 (2015).

    Mohammad Abdollahi, Mohammad Ali Faramarzi, Alireza Foroumadi, Kambiz Gilani, Hossein Khalili, Mahnaz Khanavi, Ali Akbar Moghadamnia, Morteza Mahmoudi, Shekoufeh Nikfar, Ali Nokhodchi, Roja Rahimi, Mohammad Reza Rouini and Alireza Vatanara

    DARU Journal of Pharmaceutical Sciences 2016 24:5

    Published on: 24 February 2016

  3. Research article

    A novel approach for inventory problem in the pharmaceutical supply chain

    In pharmaceutical enterprises, keeping up with global market conditions is possible with properly selected supply chain management policies. Generally; demand-driven classical supply chain model is used in the...

    Gökçe Candan and Harun Reşit Yazgan

    DARU Journal of Pharmaceutical Sciences 2016 24:4

    Published on: 24 February 2016

  4. Review article

    Women-only drug treatment services and needs in Iran: the first review of current literature

    Iran (Persia) has a women-only drug treatment system. However, literature is not documented. The current study aimed to review the development of women-only drug treatment and harm reduction services (WODTHRS) an...

    Zahra Alam-mehrjerdi, Reza Daneshmand, Mercedeh Samiei, Roya Samadi, Mohammad Abdollahi and Kate Dolan

    DARU Journal of Pharmaceutical Sciences 2016 24:3

    Published on: 18 February 2016

    The Erratum to this article has been published in DARU Journal of Pharmaceutical Sciences 2016 24:19

  5. Research article

    Comparative Pharmacokinetics of three major bioactive components in rats after oral administration of Typhae Pollen-Trogopterus Feces drug pair before and after compatibility

    Typhae Pollen (TP) and Trogopterus Feces (TF) are well-known traditional medicine in china which widely used for thousands of years as drug pair called Shixiao San for treatment of blood stasis syndrome, speci...

    Huiting Zeng, Ping Xue, Shulan Su, Xiaochen Huang, Erxin Shang, Jianming Guo, Dawei Qian, Yuping Tang and Jin-ao Duan

    DARU Journal of Pharmaceutical Sciences 2016 24:2

    Published on: 20 January 2016

  6. Research article

    Two COX-2 inhibitors induce apoptosis in human erythroleukemia K562cells by modulating NF-κB and FHC pathways

    Leukemia is distinguished by abnormal proliferation of leukocytes. Although there has been some progress in developing novel cancer therapies, no significant improvement was observed in the overall survival ra...

    Shaghayegh Norouzi, Mahnaz Norouzi, Mohsen Amini, Amir Amanzadeh, Mohamad Nabiuni, Saeed Irian and Mona Salimi

    DARU Journal of Pharmaceutical Sciences 2016 24:1

    Published on: 7 January 2016

  7. Research Article

    Cost-effectiveness and cost-utility analysis of OTC use of simvastatin 10 mg for the primary prevention of myocardial infarction in Iranian men

    Several clinical trials and meta-analyses have shown the advantageous effects of statins in populations with different levels of cardiovascular disease (CVD) risk. Considering the increasing cardiovascular ris...

    Mohammadreza Amirsadri and Abbas Hassani

    DARU Journal of Pharmaceutical Sciences 2015 23:56

    Published on: 30 December 2015

  8. Research article

    Cardanol isolated from Thai Apis mellifera propolis induces cell cycle arrest and apoptosis of BT-474 breast cancer cells via p21 upregulation

    Cardanol was previously reported to be an antiproliferative compound purified from Thai Apis mellifera propolis. By morphology, it could induce the cell death to many cancer cell lines but not the control (non-tr...

    Sureerat Buahorm, Songchan Puthong, Tanapat Palaga, Kriengsak Lirdprapamongkol, Preecha Phuwapraisirisan, Jisnuson Svasti and Chanpen Chanchao

    DARU Journal of Pharmaceutical Sciences 2015 23:55

    Published on: 22 December 2015

  9. Research article

    Comparison of the effects of Crataegus oxyacantha extract, aerobic exercise and their combination on the serum levels of ICAM-1 and E-Selectin in patients with stable angina pectoris

    Adhesion molecules play an important role in the development and progression of coronary atherosclerosis. The aim of this study was comparing the effect of Cratagol herbal tablet, aerobic exercise and their co...

    Leila Jalaly, Gholamreza Sharifi, Mohammad Faramarzi, Alireza Nematollahi, Mahmoud Rafieian-kopaei, Masoud Amiri and Fariborz Moattar

    DARU Journal of Pharmaceutical Sciences 2015 23:54

    Published on: 19 December 2015

  10. Review article

    Blessings in disguise: a review of phytochemical composition and antimicrobial activity of plants belonging to the genus Eryngium

    Medicinal and edible plants play a crucial role in the prevention and/or mitigation of different human diseases from ancient times to today. In folk medicine, there are different plants used for infectious dis...

    Sinem Aslan Erdem, Seyed Fazel Nabavi, Ilkay Erdogan Orhan, Maria Daglia, Morteza Izadi and Seyed Mohammad Nabavi

    DARU Journal of Pharmaceutical Sciences 2015 23:53

    Published on: 14 December 2015

  11. Research article

    Preventive effects of phenylethanol glycosides from Cistanche tubulosa on bovine serum albumin-induced hepatic fibrosis in rats

    Cistanche tubulosa is a traditional Chinese herbal medicine that is widely used for regulating immunity. Phenyl ethanol glycosides (CPhGs) from this plant are the primarily efficacious...

    Shu-Ping You, Jun Zhao, Long Ma, Mukaram Tudimat, Shi-Lei Zhang and Tao Liu

    DARU Journal of Pharmaceutical Sciences 2015 23:52

    Published on: 9 December 2015

  12. Editorial

    The Persian methamphetamine use in methadone treatment in Iran: implication for prevention and treatment in an upper-middle income country

    As the most populated Persian Gulf country in West Asia, methamphetamine use in methadone maintenance treatment (MMT) is a new health concern in Iran. Methamphetamine use in MMT can originate in methadone misc...

    Zahra Alam-mehrjerdi and Mohammad Abdollahi

    DARU Journal of Pharmaceutical Sciences 2015 23:51

    Published on: 17 November 2015

  13. Research article

    Improved intraocular bioavailability of ganciclovir by mucoadhesive polymer based ocular microspheres: development and simulation process in Wistar rats

    The poor ocular bioavailability of the conventional eye drops is due to lack of corneal permeability, nasolacrimal drainage and metabolic degradation. To overcome this issue, drug encapsulated in mucoadhesive ...

    Usha Ganganahalli Kapanigowda, Sree Harsha Nagaraja, Balakeshwa Ramaiah and Prakash Rao Boggarapu

    DARU Journal of Pharmaceutical Sciences 2015 23:49

    Published on: 24 October 2015

  14. Research article

    A new formulation of cannabidiol in cream shows therapeutic effects in a mouse model of experimental autoimmune encephalomyelitis

    The present study was designed to investigate the efficacy of a new formulation of alone, purified cannabidiol (CBD) (>98 %), the main non-psychotropic cannabinoid of Cannabis sativa, as a topical treatment in...

    Sabrina Giacoppo, Maria Galuppo, Federica Pollastro, Gianpaolo Grassi, Placido Bramanti and Emanuela Mazzon

    DARU Journal of Pharmaceutical Sciences 2015 23:48

    Published on: 21 October 2015

  15. Review article

    Immunomodulatory effect of hypertonic saline in hemorrhagic shock

    Multiple organ dysfunction syndrome (MODS) and nosocomial infection following trauma-hemorrhage are among the most important causes of mortality in hemorrhagic shock patients. Dysregulation of the immune syste...

    Javad Motaharinia, Farhad Etezadi, Azadeh Moghaddas and Mojtaba Mojtahedzadeh

    DARU Journal of Pharmaceutical Sciences 2015 23:47

    Published on: 5 October 2015

  16. Research article

    Repaglinide-loaded solid lipid nanoparticles: effect of using different surfactants/stabilizers on physicochemical properties of nanoparticles

    Repaglinide is an efficient anti-diabetic drug which is prescribed widely as multi-dosage oral daily regimens. Due to the low compliance inherent to each multi-dosage regimen, development of prolonged-release ...

    Hossein Ali Ebrahimi, Yousef Javadzadeh, Mehrdad Hamidi and Mohammad Barzegar Jalali

    DARU Journal of Pharmaceutical Sciences 2015 23:46

    Published on: 21 September 2015

  17. Research Article

    The impact of polymer coatings on magnetite nanoparticles performance as MRI contrast agents: a comparative study

    Superparamagnetic iron oxide nanoparticles (SPIONs) are the most commonly used negative MRI contrast agent which affect the transverse (T2) relaxation time. The aim of the present study was to investigate the imp...

    Maryam Khalkhali, Kobra Rostamizadeh, Somayeh Sadighian, Farhad Khoeini, Mehran Naghibi and Mehrdad Hamidi

    DARU Journal of Pharmaceutical Sciences 2015 23:45

    Published on: 17 September 2015

  18. Review article

    Zinc and diabetes mellitus: understanding molecular mechanisms and clinical implications

    Diabetes mellitus is a leading cause of morbidity and mortality worldwide. Studies have shown that Zinc has numerous beneficial effects in both type-1 and type-2 diabetes. We aim to evaluate the literature on ...

    Priyanga Ranasinghe, Shehani Pigera, Priyadarshani Galappatthy, Prasad Katulanda and Godwin R. Constantine

    DARU Journal of Pharmaceutical Sciences 2015 23:44

    Published on: 17 September 2015

  19. Research article

    Protection by beta-Hydroxybutyric acid against insulin glycation, lipid peroxidation and microglial cell apoptosis

    Diabetes mellitus is characterized jointly by hyperglycemia and hyperinsulinemia that make insulin more prone to be glycated and evolve insulin advanced glycation end products (Insulin- AGE). Here, we report t...

    Manijheh Sabokdast, Mehran Habibi-Rezaei, Ali Akbar Moosavi-Movahedi, Maryam Ferdousi, Effat Azimzadeh-Irani and Najmeh Poursasan

    DARU Journal of Pharmaceutical Sciences 2015 23:42

    Published on: 27 August 2015

  20. Research

    Effect of ethylene glycol dimethacrylate on swelling and on metformin hydrochloride release behavior of chemically crosslinked pH–sensitive acrylic acid–polyvinyl alcohol hydrogel

    The present work objective was to prepare and to observe the effect of ethylene glycol dimethacrylate on swelling and on drug release behavior of pH-sensitive acrylic acid–polyvinyl alcohol hydrogel.

    Muhammad Faheem Akhtar, Nazar Muhammad Ranjha and Muhammad Hanif

    DARU Journal of Pharmaceutical Sciences 2015 23:41

    Published on: 19 August 2015

  21. Research

    Generation of stable ARE- driven reporter system for monitoring oxidative stress

    NF-E2-related factor2 (Nrf2)-antioxidant response element (ARE) signaling pathway is the major defensive mechanism against oxidative stress and is up regulated by specific antioxidants and oxidants to comprise...

    Paria Motahari, Majid Sadeghizadeh, Mehrdad Behmanesh, Shaghayegh Sabri and Fatemeh Zolghadr

    DARU Journal of Pharmaceutical Sciences 2015 23:38

    Published on: 1 August 2015

  22. Research

    Thallium exists in opioid poisoned patients

    Thallium (Tl) is a toxic heavy metal that exists in nature. Tl poisoning (thallotoxicosis) may occur in opioid addicts. This study was designed to evaluate the frequency and level of urinary Tl in opioid abuse...

    Amir Ghaderi, Naser Vahdati-Mashhadian, Zohreh Oghabian, Valiallah Moradi, Reza Afshari and Omid Mehrpour

    DARU Journal of Pharmaceutical Sciences 2015 23:39

    Published on: 1 August 2015

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