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  1. Research article

    99mTc-radiolabeled GE11-modified peptide for ovarian tumor targeting

    Ovarian cancer is a serious threat for women health and the early diagnosis of this cancer might improves the survival rate of patients. The use of the targeted radiopharmaceuticals could be a non-invasive and...

    Najmeh Rahmanian, Seyed Jalal Hosseinimehr, Ali Khalaj, Zohreh Noaparast, Seyed Mohammad Abedi and Omid Sabzevari

    DARU Journal of Pharmaceutical Sciences 2017 25:13

    Published on: 2 May 2017

  2. Research article

    Adverse drug reactions and kinetics of cisplatin excretion in urine of patients undergoing cisplatin chemotherapy and radiotherapy for head and neck cancer: a prospective study

    Cisplatin is a high-potency anticancer agent; however, it causes significant adverse drug reactions (ADRs). Potential pharmacokinetic markers must be studied to predict or prevent cisplatin-induced ADRs and ac...

    Marília Berlofa Visacri, Eder de Carvalho Pincinato, Graziele Baldan Ferrari, Júlia Coelho França Quintanilha, Priscila Gava Mazzola, Carmen Silvia Passos Lima and Patricia Moriel

    DARU Journal of Pharmaceutical Sciences 2017 25:12

    Published on: 24 April 2017

  3. Research article

    Combination of sofosbuvir, pegylated-interferon and ribavirin for treatment of hepatitis C virus genotype 1 infection: a systematic review and meta-analysis

    Hepatitis C virus (HCV) infection is an important cause of chronic liver disease which has been affected 3% of world’s population. Some studies have shown that adding Sofosbuvir (SOF), an HCV polymerase inhibi...

    Fardin Dolatimehr, Hamidreza Karimi-Sari, Mohammad Saeid Rezaee-Zavareh, Seyed Moayed Alavian, Bita Behnava, Mohammad Gholami-Fesharaki and Heidar Sharafi

    DARU Journal of Pharmaceutical Sciences 2017 25:11

    Published on: 20 April 2017

  4. Review article

    A guide to acquired vitamin K coagulophathy diagnosis and treatment: the Russian perspective

    Physicians often come across with cases of vitamin K antagonists–dependent coagulopathy for reasons such as accidental use of the vitamin K antagonists (VKA), excessive administration of prescribed anticoagula...

    Valery V. Wojciechowski, Daniela Calina, Konstantinos Tsarouhas, Alexander V. Pivnik, Alexander A. Sergievich, Vladimir V. Kodintsev, Ekaterina A. Filatova, Eren Ozcagli, Anca Oana Docea, Andreea Letitia Arsene, Eliza Gofita, Christina Tsitsimpikou, Aristidis M. Tsatsakis and Kirill S. Golokhvast

    DARU Journal of Pharmaceutical Sciences 2017 25:10

    Published on: 17 April 2017

  5. Editorial

    Health risks associated with the pharmaceuticals in wastewater

    The overwhelming population growth in recent decades and water crisis along with limited and uneven geographical distribution of fresh water resources is a growing challenge for the economic and human developm...

    Nasser Nassiri Koopaei and Mohammad Abdollahi

    DARU Journal of Pharmaceutical Sciences 2017 25:9

    Published on: 12 April 2017

  6. Research article

    Improvement of memory and learning by intracerebroventricular microinjection of T3 in rat model of ischemic brain stroke mediated by upregulation of BDNF and GDNF in CA1 hippocampal region

    Ischemic stroke is a common leading cause of death and disability with lack of effective therapies. In this study, T3 was intra-ventricularly injected to evaluate gene expression and protein concentration of a...

    Tahmineh Mokhtari, Mohammad Akbari, Fatemeh Malek, Iraj Ragerdi Kashani, Tayebeh Rastegar, Farshid Noorbakhsh, Mahmoud Ghazi-Khansari, Fatemeh Attari and Gholamreza Hassanzadeh

    DARU Journal of Pharmaceutical Sciences 2017 25:4

    Published on: 15 February 2017

  7. Research article

    Simultaneous detection of bovine and porcine DNA in pharmaceutical gelatin capsules by duplex PCR assay for Halal authentication

    In the pharmaceutical industry, hard- and soft-shelled capsules are typically made from gelatin, commonly derived from bovine and porcine sources. To ensure that pharmaceutical products comply with halal regul...

    Jafar Nikzad, Soraya Shahhosseini, Maryam Tabarzad, Nastaran Nafissi-Varcheh and Maryam Torshabi

    DARU Journal of Pharmaceutical Sciences 2017 25:3

    Published on: 14 February 2017

  8. Review article

    New horizons in treatment of osteoporosis

    Prevalence of osteoporosis is increasing both in developed and developing countries. Due to rapid growth in the burden and cost of osteoporosis, worldwide, it seems reasonable to focus on the reduction of frac...

    Ozra Tabatabaei-Malazy, Pooneh Salari, Patricia Khashayar and Bagher Larijani

    DARU Journal of Pharmaceutical Sciences 2017 25:2

    Published on: 7 February 2017

  9. Research article

    Budget impact analysis of vaccination against Haemophilus influenzae type b as a part of a Pentavalent vaccine in the childhood immunization schedule of Iran

    Health decision makers need to know the impact of the development of a new intervention on the public health and health care costs so that they can plan for economic and financial objectives. The aim of this s...

    Fatemeh Teimouri, Abbas Kebriaeezadeh, Seyed Mohsen Zahraei, Mohammadmahdi Gheiratian and Shekoufeh Nikfar

    DARU Journal of Pharmaceutical Sciences 2017 25:1

    Published on: 14 January 2017

  10. Editorial

    Opportunities and obstacles to the development of nanopharmaceuticals for human use

    Pharmaceutical nanotechnology has generated breakthrough developments in improving health care and human life from its emergence. The biomaterials employed mainly aim at improving drug delivery systems, imagin...

    Nasser Nassiri Koopaei and Mohammad Abdollahi

    DARU Journal of Pharmaceutical Sciences 2016 24:23

    Published on: 6 October 2016

    The Erratum to this article has been published in DARU Journal of Pharmaceutical Sciences 2016 24:25

  11. Research article

    Effects of developmental exposure to silver in ionic and nanoparticle form: A study in rats

    Evaluations of silver in both nanoparticle (Ag-NPs) and ionic forms indicate some adverse effects on living organisms, but little is known about their potential for developmental toxicity. In this study, devel...

    Mohammad Charehsaz, Karin Sørig Hougaard, Hande Sipahi, Asiye Işın Doğan Ekici, Çiğdem Kaspar, Mustafa Culha, Ülkü Ündeğer Bucurgat and Ahmet Aydin

    DARU Journal of Pharmaceutical Sciences 2016 24:24

    Published on: 6 October 2016

  12. Research article

    Pharmacokinetics of calycopterin and xanthmicrol, two polymethoxylated hydroxyflavones with anti-angiogenic activities from Dracocephalum kotschyi Bioss

    Recently flavonoids have attracted the attention of researchers in the fight against cancer. Calycopterin and xanthomicrol, are two polymethoxylated flavonoids found in the aerial parts of Dracocephalum kotschyi ...

    Seyedeh-Somayeh Zamani, Mohsen Hossieni, Mahmoud Etebari, Pirooz Salehian and Soltan Ahmad Ebrahimi

    DARU Journal of Pharmaceutical Sciences 2016 24:22

    Published on: 4 October 2016

  13. Research article

    Fabrication and biological evaluation of chitosan coated hyaluronic acid-docetaxel conjugate nanoparticles in CD44+ cancer cells

    Hyaluronic acid (HA) has been used for target-specific drug delivery because of strong affinity to CD44, a marker in which overexpressed in cancer cells and cancer stem cells. Conjugation of HA to the cytotoxi...

    Nazanin Shabani Ravari, Navid Goodarzi, Farhad Alvandifar, Mohsen Amini, Effat Souri, Mohammad Reza Khoshayand, Zahra Hadavand Mirzaie, Fatemeh Atyabi and Rassoul Dinarvand

    DARU Journal of Pharmaceutical Sciences 2016 24:21

    Published on: 29 July 2016

  14. Letter to the Editor

    Aspirin use and bleeding volume in skin cancer patients undergoing surgery: a randomized controlled trial

    We investigated the occurrence of bleeding complications in patients who underwent skin tumor surgery and compared it between Aspirin users and a placebo control group. In this double blind randomized controll...

    Arman Engheta, Shahryar Hadadi Abianeh, Ali Atri and Mehdi Sanatkarfar

    DARU Journal of Pharmaceutical Sciences 2016 24:20

    Published on: 28 July 2016

  15. Research article

    Expression, purification and biological activity assessment of romiplostim biosimilar peptibody

    Romiplostim is a peptibody analogue of thrombopoietin (TPO) which regulates platelet production. This molecule consists of two main parts: Peptide sequences which like wild type TPO, mimics stimulation of TPO ...

    Shima Fayaz, Pezhman Fard-Esfahani, Majid Golkar, Mojgan Allahyari and Sedigheh Sadeghi

    DARU Journal of Pharmaceutical Sciences 2016 24:18

    Published on: 11 July 2016

  16. Research article

    Crocin suppresses multidrug resistance in MRP overexpressing ovarian cancer cell line

    Crocin, one of the main constituents of saffron extract, has numerous biological effects such as anti-cancer effects. Multidrug resistance-associated proteins 1 and 2 (MRP1 and MRP2) are important elements in ...

    Shadi Mahdizadeh, Gholamreza Karimi, Javad Behravan, Sepideh Arabzadeh, Hermann Lage and Fatemeh Kalalinia

    DARU Journal of Pharmaceutical Sciences 2016 24:17

    Published on: 24 June 2016

  17. Research article

    Effects of phloretin on oxidative and inflammatory reaction in rat model of cecal ligation and puncture induced sepsis

    Sepsis is a debilitating systemic disease and described as a severe and irregular systemic inflammatory reaction syndrome (SIRS) against infection. We employed CLP (Cecal Ligation and Puncture) model in rats t...

    Mehdi Aliomrani, Mohammad Reza Sepand, Hamid Reza Mirzaei, Ali Reza kazemi, Saeid Nekonam and Omid Sabzevari

    DARU Journal of Pharmaceutical Sciences 2016 24:15

    Published on: 6 May 2016

  18. Research article

    High azithromycin concentration in lungs by way of bovine serum albumin microspheres as targeted drug delivery: lung targeting efficiency in albino mice

    Following administration, the antibiotic travels freely through the body and also accumulates in other parts apart from the infection site. High dosage and repeated ingestion of antibiotics in the treatment of...

    Balakeshwa Ramaiah, Sree Harsha Nagaraja, Usha Ganganahalli Kapanigowda, Prakash Rao Boggarapu and Rajarajan Subramanian

    DARU Journal of Pharmaceutical Sciences 2016 24:14

    Published on: 5 May 2016

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